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MISSION TO ZYXX is an improvised science fiction podcast following a team of ambassadors as they attempt to establish diplomatic relations with planets in the remote and chaotic ZYXX QUADRANT of the TREMILLION SECTOR. They work for the benevolent and harmonious FEDERATED ALLIANCE, which has recently defeated the evil GALACTIC MONARCHY. The Federated Alliance is definitely less evil.  

The Alliance's newest recruit is AMBASSADOR PLECK DECKSETTER, a naive, gung-ho farm boy whose crew includes trusty, know-it-all droid C-53, and hulking, omnisexual security officer DAR.  They travel aboard the outdated, sentient starship THE BARGAREAN JADE - aka BARGIE - who has as many ex-husbands as stories about her glory days. Their mission is nominally overseen by JUNIOR MISSIONS OPERATIONS MANAGER NERMUT BUNDALOY, a striving, entry-level, lizard-bird bureaucrat yearning for respect. 

Well, that at least describes Season 1. There are a total of 5 seasons.

An all-new prequel miniseries THE YOUNG OLD DERF CHRONICLES premiered on December 3, 2025, after winning Best Audio Fiction at the 2025 Tribeca Festival. Derf episodes alternate with episodes of MISSION TO D-SYXX, an actual play D&D campaign featuring the characters from Mission to Zyxx Episode 419.

Mission to Zyxx is a proud member of the MAXIMUM FUN podcast network, whose members made the show possible. JOIN THEM.